PH-HG-005-5
PH-HG-005-5 (compound 16c) is a derivative of SN-38 (HY-13704) and can be used as Drug-Linker Conjugates for ADC. PH-HG-005-5 can conjugate to targeting peptides for ADCs synthesis[1].
Product Specifications
CAS Number
[2810895-93-1]
UNSPSC
12352005
Target
Drug-Linker Conjugates for ADC
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ph-hg-005-5.html
Purity
99.51
Solubility
DMSO : 150 mg/mL (ultrasonic)
Smiles
CC(C)[C@H](N)C(N[C@@H](CCCNC(N)=O)C(NC(C=C1)=CC=C1COC(O[C@]2(C3=C(COC2=O)C(N4C(C(C(C4)=C(C5=C6)CC)=NC5=CC=C6O)=C3)=O)CC)=O)=O)=O
Molecular Formula
C41H47N7O10
Molecular Weight
797.85
References & Citations
[1]Chen Jian, et al. EphA2 bicyclic peptide ligand and conjugate thereof. World Intellectual Property Organization, WO2023061482 A1. 2023-04-20.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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