H-NTPDase-IN-4

H-NTPDase-IN-4 (compound 4c) is a pan-inhibitor of NTPDase with IC50s of 3.58 μM (h-NTPDase1), 10.21 μM (h-NTPDase2), 0.13 μM (h-NTPDase3), 13.57 μM (h- NTPDase8) .

Product Specifications

CAS Number

[2939933-09-0]

UNSPSC

12352005

Target

NTPDase

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/h-ntpdase-in-4.html

Purity

98.64

Solubility

DMF : 100 mg/mL (ultrasonic)

Smiles

FC(C1=CC(C2=NC=NC3=C2SC=C3C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)=CC(C(F)(F)F)=C1)(F)F

Molecular Formula

C22H8F12N2S

Molecular Weight

560.36

References & Citations

[1]Zaman G, Ullah S, Uzair M, et al. Synthesis of Thieno [3, 2‐d] pyrimidine Derivatives through Sequential SNAr and Suzuki Reactions as Selective h‐NTPDases Inhibitors[J]. ChemMedChem, 2023: e202300165.