9-Deazaguanine
9-Deazaguanine is a nucleoside analog with potent inhibitory activity against purine nucleoside phosphorylase (PNP) [1].
Product Specifications
CAS Number
[65996-58-9]
UNSPSC
12352005
Hazard Statement
H226, H302, H315, H319, H373
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/9-deazaguanine.html
Purity
99.01
Solubility
DMSO : 3.33 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
NC(NC1=O)=NC2=C1NC=C2
Molecular Formula
C6H6N4O
Molecular Weight
150.14
Precautions
H226, H302, H315, H319, H373
References & Citations
[1]Beata Wielgus-Kutrowska, et al. Trimeric purine nucleoside phosphorylase: exploring postulated one-third-of-the-sites binding in the transition state. Bioorg Med Chem. 2012 Nov 15;20 (22) :6758-69.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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