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9-Deazaguanine

9-Deazaguanine is a nucleoside analog with potent inhibitory activity against purine nucleoside phosphorylase (PNP) [1].

Product Specifications

CAS Number

[65996-58-9]

UNSPSC

12352005

Hazard Statement

H226, H302, H315, H319, H373

Target

DNA/RNA Synthesis

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/9-deazaguanine.html

Purity

99.01

Solubility

DMSO : 3.33 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

NC(NC1=O)=NC2=C1NC=C2

Molecular Formula

C6H6N4O

Molecular Weight

150.14

Precautions

H226, H302, H315, H319, H373

References & Citations

[1]Beata Wielgus-Kutrowska, et al. Trimeric purine nucleoside phosphorylase: exploring postulated one-third-of-the-sites binding in the transition state. Bioorg Med Chem. 2012 Nov 15;20 (22) :6758-69.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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