Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Neuropeptide W-30 (rat)

Neuropeptide W-30 (rat) is an important stress mediator in the central nervous system that modulates the hypothalamus-pituitary-adrenal (HPA) axis and sympathetic outflow. Neuropeptide W-30 (rat) is an endogenous ligand for the two structurally related orphan G-protein-coupled receptors (GPCRs) GPR7 and GPR8. NPW-30 activates and binds to both GPR7 and GPR8 at similar effective doses[1][2][3].

Product Specifications

CAS Number

383415-90-5

Product Name Alternative

NPW30, rat

UNSPSC

12352209

Target

Neuropeptide B/W Receptor

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/neuropeptide-w-30-rat.html

Solubility

10 mM in DMSO

Smiles

O=C([C@H]1N(CCC1)C([C@H](CO)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC(CNC([C@H](CCSC)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC(CNC([C@H](CO)NC([C@H](C)NC([C@H](CCCNC(N)=N)NC(CNC([C@H](C(C)C)NC([C@H]([C@H](O)C)NC([C@@H](NC([C@@H](NC([C@H](CCCNC(N)=N)NC([C@H]2N(CCC2)C([C@H](CO)NC([C@H](C)NC([C@H](C(C)C)NC([C@@H](NC([C@H](CCCCN)NC([C@@H](NC([C@@H](N)CC3=CNC4=CC=CC=C34)=O)CC5=CC=C(C=C5)O)=O)=O)CC6=CN=CN6)=O)=O)=O)=O)=O)=O)CC7=CC=C(C=C7)O)=O)CC8=CN=CN8)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)N[C@@H](CC9=CC=C(C=C9)O)C(N[C@@H](CC(C)C)C(N[C@H](C(O)=O)CC%10=CNC%11=CC=CC=C%10%11)=O)=O

Molecular Formula

C165H249N49O38S

Molecular Weight

3559.11

References & Citations

[1]Makoto Kawasaki, et al. Centrally administered neuropeptide W-30 activates magnocellular neurosecretory cells in the supraoptic and paraventricular nuclei with neurosecretion in rats. J Endocrinol. 2006 Aug;190 (2) :213-23.|[2]Nan-Shou Yu, et al. Effects of intracerebroventricular administration of neuropeptide W30 on neurons in the hypothalamic paraventricular nucleus in the conscious rat. Neurosci Lett. 2007 Mar 26;415 (2) :140-5.|[3]Yukio Shimomura, et al. Identification of neuropeptide W as the endogenous ligand for orphan G-protein-coupled receptors GPR7 and GPR8. J Biol Chem. 2002 Sep 27;277 (39) :35826-32.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

CD86 (BU63), CF647 conjugate, 0.1mg/mL
BNC470193-100 1x 100 µL

CD86 (BU63), CF647 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
CD20 (B9E9), CF594 conjugate, 0.1mg/mL
BNC940160-100 1x 100 µL

CD20 (B9E9), CF594 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
CD50 (ICAM-3) (101-1D2), CF488A conjugate, 0.1mg/mL
BNC880177-500 1x 500 µL

CD50 (ICAM-3) (101-1D2), CF488A conjugate, 0.1mg/mL

Sign In for Pricing
View Details
WIPI2 (2A2), CF405S conjugate, 0.1mg/mL
BNC042904-100 1x 100 µL

WIPI2 (2A2), CF405S conjugate, 0.1mg/mL

Sign In for Pricing
View Details
TRIM29 (TRIM29/1042), CF640R conjugate, 0.1mg/mL
BNC401042-100 1x 100 µL

TRIM29 (TRIM29/1042), CF640R conjugate, 0.1mg/mL

Sign In for Pricing
View Details
Progesterone Receptor (PR484), CF488A conjugate, 0.1mg/mL
BNC880484-100 1x 100 µL

Progesterone Receptor (PR484), CF488A conjugate, 0.1mg/mL

Sign In for Pricing
View Details