(Rac) -AZD 6482

(Rac) -AZD 6482 ((Rac) -KIN-193) is the racemate of AZD 6482. AZD 6482 is a potent and selective p110β inhibitor with an IC50 of 0.69 nM.

Product Specifications

CAS Number

[663620-70-0]

Product Name Alternative

(Rac) -KIN-193

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Autophagy; PI3K

Type

Reference compound

Related Pathways

Autophagy; PI3K/Akt/mTOR

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/rac-azd-6482.html

Purity

98.51

Solubility

DMSO : 33.33 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C1N2C(C(C(C)NC3=CC=CC=C3C(O)=O)=CC(C)=C2)=NC(N4CCOCC4)=C1

Molecular Formula

C22H24N4O4

Molecular Weight

408.45

Precautions

H302, H315, H319, H335

References & Citations

[1]Ni J, et al. Functional characterization of an isoform-selective inhibitor of PI3K-p110β as a potential anticancer agent. Cancer Discov. 2012 May;2 (5) :425-33.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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