(Rac) -AZD 6482
(Rac) -AZD 6482 ((Rac) -KIN-193) is the racemate of AZD 6482. AZD 6482 is a potent and selective p110β inhibitor with an IC50 of 0.69 nM.
Product Specifications
CAS Number
[663620-70-0]
Product Name Alternative
(Rac) -KIN-193
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Autophagy; PI3K
Type
Reference compound
Related Pathways
Autophagy; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rac-azd-6482.html
Purity
98.51
Solubility
DMSO : 33.33 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1N2C(C(C(C)NC3=CC=CC=C3C(O)=O)=CC(C)=C2)=NC(N4CCOCC4)=C1
Molecular Formula
C22H24N4O4
Molecular Weight
408.45
Precautions
H302, H315, H319, H335
References & Citations
[1]Ni J, et al. Functional characterization of an isoform-selective inhibitor of PI3K-p110β as a potential anticancer agent. Cancer Discov. 2012 May;2 (5) :425-33.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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