(Rac)-AZD 6482
Product Specifications
UNSPSC Description
(Rac)-AZD 6482 ((Rac)-KIN-193) is the racemate of AZD 6482. AZD 6482 is a potent and selective p110β inhibitor with an IC50 of 0.69 nM.
Target Antigen
Autophagy; PI3K
Type
Reference compound
Related Pathways
Autophagy;PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rac-azd-6482.html
Purity
98.51
Solubility
DMSO : 33.33 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
O=C1N2C(C(C(C)NC3=CC=CC=C3C(O)=O)=CC(C)=C2)=NC(N4CCOCC4)=C1
Molecular Weight
408.45
References & Citations
[1]Ni J, et al. Functional characterization of an isoform-selective inhibitor of PI3K-p110β as a potential anticancer agent. Cancer Discov. 2012 May;2(5):425-33.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-75124/Rac-AZD-6482-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-75124/Rac-AZD-6482-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
663620-70-0
Available Sizes
Curated Selection
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