SARS-CoV-2 (COVID-19) S1 protein, Fc Tag
SARS-CoV-2 S1 protein, Fc Tag (S1N-C5255) is expressed from human 293 cells (HEK293) . It contains AA Val 16 - Arg 685 (Accession # QHD43416.1) .
Product Specifications
Background
It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
Specifications
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 101.5 kDa. The protein migrates as 130-150 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
QHD43416.1
Expression Region
Val 16 - Arg 685
Host
HEK293
Target
Spike S1
Conjugation
Unconjugated
Tag
C-Fc
Source
SARS-CoV-2
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
95%
Bioactivity
Immobilized Biotinylated Human ACE2, His,Avitag (Cat. No. AC2-H82E6) at 1 μg/mL (100 μL/well) on Streptavidin (Cat. No. STN-N5116) precoated (0.5 μg/well) plate,can bind SARS-CoV-2 S1 protein, Fc Tag (Cat. No. S1N-C5255) with a linear range of 0.4-6 ng/mL (QC tested).
Format
Powder
Buffer
Tris, Glycine and NaCl, pH7.5
Additives
Trehalose
Molecular Weight
101.5 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
100ug*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/S1N-C5255.pdf
Species
SARS-CoV-2
Curated Selection
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