Indicine N-oxide

Indicine N-oxide (NSC 132319), a pyrrolizidine alkaloid, is an antitumor agent for pediatric cancer and solid tumors research[1].

Product Specifications

CAS Number

[41708-76-3]

Product Name Alternative

(+) -Indicine N-oxide; NSC 132319

UNSPSC

12352005

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/indicine-n-oxide.html

Solubility

10 mM in DMSO

Smiles

CC(C)[C@]([C@@H](O)C)(O)C(OCC1=CC[N+]2([O-])[C@@]1([H])[C@@H](CC2)O)=O

Molecular Formula

C15H25NO6

Molecular Weight

315.36

References & Citations

[1]V M Whitehead, et al. Phase I trial of indicine-N-oxide in children with leukemia and solid tumors: a Pediatric Oncology Group study. Cancer Chemother Pharmacol. 1990;26 (5) :377-9.|[2]J S Kovach, et al. Toxicity and pharmacokinetics of a pyrrolizidine alkaloid, indicine N-oxide, in humans. Cancer Res. 1979 Nov;39 (11) :4540-4.