Indicine N-oxide
Indicine N-oxide (NSC 132319), a pyrrolizidine alkaloid, is an antitumor agent for pediatric cancer and solid tumors research[1].
Product Specifications
CAS Number
[41708-76-3]
Product Name Alternative
(+) -Indicine N-oxide; NSC 132319
UNSPSC
12352005
Target
Others
Type
Natural Products
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/indicine-n-oxide.html
Solubility
10 mM in DMSO
Smiles
CC(C)[C@]([C@@H](O)C)(O)C(OCC1=CC[N+]2([O-])[C@@]1([H])[C@@H](CC2)O)=O
Molecular Formula
C15H25NO6
Molecular Weight
315.36
References & Citations
[1]V M Whitehead, et al. Phase I trial of indicine-N-oxide in children with leukemia and solid tumors: a Pediatric Oncology Group study. Cancer Chemother Pharmacol. 1990;26 (5) :377-9.|[2]J S Kovach, et al. Toxicity and pharmacokinetics of a pyrrolizidine alkaloid, indicine N-oxide, in humans. Cancer Res. 1979 Nov;39 (11) :4540-4.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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