SR-16434

SR-16434 is a nociceptin/orphanin FQ (NOP) /μ-opioid receptor partial agonist, with high binding affinity (NOP receptor Ki=7.49; μ-Opioid receptor Ki=2.70) . SR-16434 can relieve pain[1].

Product Specifications

CAS Number

[857262-16-9]

Product Name Alternative

SR-16435 (free base)

UNSPSC

12352005

Target

Opioid Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/sr-16435.html

Solubility

10 mM in DMSO

Smiles

O=C1N(C2CCN(C3C4CCCC3CCC4)CC2)C5=C(C=CC=C5)C1

Molecular Formula

C22H30N2O

Molecular Weight

338.49

References & Citations

[1]Khroyan TV, et al. SR 16435 [1- (1- (bicyclo[3.3.1]nonan-9-yl) piperidin-4-yl) indolin-2-one], a novel mixed nociceptin/orphanin FQ/mu-opioid receptor partial agonist: analgesic and rewarding properties in mice. J Pharmacol Exp Ther. 2007;320 (2) :934-943.