SR-16434
SR-16434 is a nociceptin/orphanin FQ (NOP) /μ-opioid receptor partial agonist, with high binding affinity (NOP receptor Ki=7.49; μ-Opioid receptor Ki=2.70) . SR-16434 can relieve pain[1].
Product Specifications
CAS Number
857262-16-9
Product Name Alternative
SR-16435 (free base)
UNSPSC
12352005
Target
Opioid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sr-16435.html
Solubility
10 mM in DMSO
Smiles
O=C1N(C2CCN(C3C4CCCC3CCC4)CC2)C5=C(C=CC=C5)C1
Molecular Formula
C22H30N2O
Molecular Weight
338.49
References & Citations
[1]Khroyan TV, et al. SR 16435 [1- (1- (bicyclo[3.3.1]nonan-9-yl) piperidin-4-yl) indolin-2-one], a novel mixed nociceptin/orphanin FQ/mu-opioid receptor partial agonist: analgesic and rewarding properties in mice. J Pharmacol Exp Ther. 2007;320 (2) :934-943.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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