2 (5H) -Furanone

2 (5H) -Furanone (γ-Crotonolactone) is an endogenous metabolite. 2 (5H) -Furanone is present in a wide variety of biologically active natural products. 2 (5H) -Furanone can undergo oraganocatalytic asymmetric direct vinylogous aldo reactions to provide diastereomerically and enantiomerically enriched 5-substituted 2 (5H) furanones[1][2].

Product Specifications

CAS Number

[497-23-4]

Product Name Alternative

γ-Crotonolactone

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/2-5h-furanone.html

Purity

99.94

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1OCC=C1

Molecular Formula

C4H4O2

Molecular Weight

84.07

Precautions

H302, H315, H319, H335

References & Citations

[1]Ahmed Hashem and Erich Kleinpeter, et al., The Chemistry of 2 (5H) -Furanones, Advances in Heterocyclic Chemistry, Academic Press, Volume 81, 2001, Pages 107-165.|[2]Sunil V. Pansare and Eldho K. Paul, Organocatalytic asymmetric direct vinylogous aldol reactions of γ-crotonolactone with aromatic aldehydes. RSC, Issue 3, 2011.