Glycyl-L-histidyl-L-lysine
Glycyl-L-histidyl-L-lysine is a tripeptide consisting of glycine, L-histidine and L-lysine residues joined in sequence. Glycyl-L-histidyl-L-lysine is a hepatotropic immunosuppressor and shows anxiolytic effect. Glycyl-L-histidyl-L-lysine and its copper complexes show good skin tolerance[1][2][3].
Product Specifications
CAS Number
49557-75-7
Product Name Alternative
GHK; Tripeptide-1
UNSPSC
12352209
Hazard Statement
H302, H315, H319, H335
Target
Others
Type
Peptides
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/glycyl-l-histidyl-l-lysine.html
Purity
99.89
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
NCCCC[C@@H](C(O)=O)NC([C@H](CC1=CNC=N1)NC(CN)=O)=O
Molecular Formula
C14H24N6O4
Molecular Weight
340.38
Precautions
H302, H315, H319, H335
References & Citations
[1]Arkadiusz Gruchlik, et al. Effect of Gly-Gly-His, Gly-His-Lys and their copper complexes on TNF-alpha-dependent IL-6 secretion in normal human dermal fibroblasts. Acta Pol Pharm. 2012 Nov-Dec;69 (6) :1303-6.|[2]M Yu Smakhtin, et al. Tripeptide Gly-His-Lys is a hepatotropic immunosuppressor. Bull Exp Biol Med. 2002 Jun;133 (6) :586-7.|[3]I Bobyntsev, et al. Anxiolytic effects of Gly-His-Lys peptide and its analogs. Bull Exp Biol Med. 2015 Apr;158 (6) :726-8.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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