(R) -L 888607
(R) -L 888607 is the isomer of L 888607 (HY-111271), and can be used as an experimental control. L 888607 is a potent, selective, stable and orally active CRTH2 agonist. L 888607 has high affinity for the human CRTH2 receptor with a Ki value of 4 nM. L 888607 can be used for the research of several physiological events and metabolite[1].
Product Specifications
CAS Number
[2446042-90-4]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Drug Isomer; Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/r-l-888607.html
Concentration
10mM
Purity
99.69
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(O)C[C@H]1CCN2C1=C(SC3=CC=C(Cl)C=C3)C4=C2C=C(F)C=C4
Molecular Formula
C19H15ClFNO2S
Molecular Weight
375.84
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Gervais FG, Identification of a potent and selective synthetic agonist at the CRTH2 receptor. Mol Pharmacol. 2005 Jun;67 (6) :1834-9.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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