Dehydrovomifoliol
Dehydrovomifoliol is a AKT/mTOR dual inhibitor. Dehydrovomifoliol reduces lipid accumulation and lipogenesis by inhibiting the AKT/mTOR signaling pathway. Dehydrovomifoliol is used in nonalcoholic fatty liver disease research (NAFLD) .
Product Specifications
CAS Number
[39763-33-2]
UNSPSC
12352211
Target
Akt; mTOR
Type
Natural Products
Related Pathways
PI3K/Akt/mTOR
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/dehydrovomifoliol.html
Purity
98.88
Solubility
10 mM in DMSO
Smiles
CC(/C=C/[C@](C(C)(C1)C)(C(C)=CC1=O)O)=O
Molecular Formula
C13H18O3
Molecular Weight
222.28
References & Citations
[1]Ma J, et al. Dehydrovomifoliol Alleviates Nonalcoholic Fatty Liver Disease via the E2F1/AKT/mTOR Axis: Pharmacophore Modeling and Molecular Docking Study. Evid Based Complement Alternat Med. 2023 Feb 1;2023:9107598.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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