Human Vaspin (Highly Pure, Recombinant)

<strong>Human Vaspin (Highly Pure, Recombinant)</strong>_x000D_ <strong>Catalog number:</strong> B2010275_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Volume/Weight:</strong> 10 ug_x000D_ <strong>pH:</strong> 7.4 upon reconstitution_x000D_ <strong>Supplied as:</strong> lyophilized powder_x000D_ <strong>Appearance:</strong> Powder_x000D_ <strong>Applications:</strong> highly pure human vaspin expressed in E. coli. This 45 kDa protein acts as a secretory adipokine and plays a protective role in insulin resistance._x000D_ <strong>Storage:</strong> -20C_x000D_ <strong>Keywords:</strong> rHuVaspin; Serpin A12; OL-64_x000D_ <strong>Grade:</strong> Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Escoté X, Gómez-Zorita S, López-Yoldi M, Milton-Laskibar I, Fernández-_x000D_ Quintela A, Martínez JA, Moreno-Aliaga MJ, Portillo MP. Role of Omentin, Vaspin,_x000D_ Cardiotrophin-1, TWEAK and NOV/CCN3 in Obesity and Diabetes Development. Int J_x000D_ Mol Sci. 2017 Aug 15;18(8):1770._x000D_ _x000D_ 2: Weiner J, Zieger K, Pippel J, Heiker JT. Molecular Mechanisms of Vaspin_x000D_ Action - From Adipose Tissue to Skin and Bone, from Blood Vessels to the Brain._x000D_ Adv Exp Med Biol. 2019;1111:159-188._x000D_ _x000D_ 3: Kurowska P, Mlyczyńska E, Dawid M, Grzesiak M, Dupont J, Rak A. The role of_x000D_ vaspin in porcine corpus luteum. J Endocrinol. 2020 Dec;247(3):283-294._x000D_ _x000D_ 4: Kurowska P, Mlyczyńska E, Dawid M, Opydo-Chanek M, Dupont J, Rak A. In Vitro_x000D_ Effects of Vaspin on Porcine Granulosa Cell Proliferation, Cell Cycle_x000D_ Progression, and Apoptosis by Activation of GRP78 Receptor and Several Kinase_x000D_ Signaling Pathways Including MAP3/1, AKT, and STAT3. Int J Mol Sci. 2019 Nov_x000D_ 19;20(22):5816._x000D_ _x000D_ 5: Kurowska P, Mlyczyńska E, Barbe A, Staub C, Gregoraszczuk E, Dupont J, Rak A._x000D_ Vaspin in the pig ovarian follicles: expression and regulation by different_x000D_ hormones. Reproduction. 2019 Aug;158(2):135-146._x000D_ _x000D_ 6: Fasshauer M, Blüher M. Adipokines in health and disease. Trends Pharmacol_x000D_ Sci. 2015 Jul;36(7):461-70._x000D_ _x000D_ 7: Dimova R, Tankova T. The role of vaspin in the development of metabolic and_x000D_ glucose tolerance disorders and atherosclerosis. Biomed Res Int._x000D_ 2015;2015:823481._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/33108071/">8: Wang J, Chen Z, Guan Z. Vaspin deficiency failed to promote the proliferation_x000D_ of BMSCs in osteoarthritis. Int J Rheum Dis. 2020 Oct 27. </a>_x000D_ _x000D_ <strong>Products Related to Vaspin (Human, Recombinant) </strong> <a href="https://moleculardepot.com/product-category/Proteins/">: Proteins</a>