SGK1-IN-4
SGK1-IN-4 (compound 17a) is a highly selective, orally active SGK1 inhibitor. SGK1-IN-4 can be used for osteoarthritis research[1].
Product Specifications
CAS Number
1628048-93-0
UNSPSC
12352005
Target
SGK
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sgk1-in-4.html
Concentration
10mM
Purity
99.80
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=S(NC(C=C1)=CC=C1C2=NC(O[C@@H]3CC[C@H](CC3)O)=C4C(NN=C4)=N2)(C5=C(C=CC(Cl)=C5)F)=O
Molecular Formula
C23H21ClFN5O4S
Molecular Weight
517.96
References & Citations
[1]Nis Halland, et al. Rational Design of Highly Potent, Selective, and Bioavailable SGK1 Protein Kinase Inhibitors for the Treatment of Osteoarthritis. J Med Chem. 2022 Jan 27;65 (2) :1567-1584.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
SGK1
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC472055-500 1x 500 µL
Carcinoembryonic Antigen (CEA) / CD66 (C66/2055R), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details