FLT3/HDAC-IN-2
FLT3/HDAC-IN-2 is (compound 25h) a FLT3/HDAC dual inhibitor. FLT3/HDAC-IN-2 has antiproliferative activity against MOLM-13 cells. FLT3/HDAC-IN-2 can be used in acute myeloid leukemia research[1].
Product Specifications
UNSPSC
12352211
Target
FLT3; HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/flt3-hdac-in-2.html
Smiles
NC(C1=C(NC2=CC=C(N3CCN(CCCCCCCC(NO)=O)CC3)C(OC)=C2)N=C(NC4CCOCC4)C(CC)=N1)=O
Molecular Formula
C31H48N8O5
Molecular Weight
612.76
References & Citations
[1]Chang Y, et al. Simultaneous inhibition of FLT3 and HDAC by novel 6-ethylpyrazine-2-Carboxamide derivatives provides therapeutic advantages in acute myelocytic leukemia. Eur J Med Chem. 2024 Sep 6;279:116847.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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