FLT3/HDAC-IN-2

FLT3/HDAC-IN-2 is (compound 25h) a FLT3/HDAC dual inhibitor. FLT3/HDAC-IN-2 has antiproliferative activity against MOLM-13 cells. FLT3/HDAC-IN-2 can be used in acute myeloid leukemia research[1].

Product Specifications

UNSPSC

12352211

Target

FLT3; HDAC

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics; Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/flt3-hdac-in-2.html

Smiles

NC(C1=C(NC2=CC=C(N3CCN(CCCCCCCC(NO)=O)CC3)C(OC)=C2)N=C(NC4CCOCC4)C(CC)=N1)=O

Molecular Formula

C31H48N8O5

Molecular Weight

612.76

References & Citations

[1]Chang Y, et al. Simultaneous inhibition of FLT3 and HDAC by novel 6-ethylpyrazine-2-Carboxamide derivatives provides therapeutic advantages in acute myelocytic leukemia. Eur J Med Chem. 2024 Sep 6;279:116847.