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Rosolic acid

Rosolic Acid is an activator of Nrf2, as well as its downstream targets. Rosolic Acid increases the levels of angiogenic factors, decreases inflammation (TNF-α and IL-1β) and apoptotic markers (CXCL10 and CCL2) . Rosolic Acid restores the function of pancreatic cells and protects endothelial cells (ECs) from endoplasmic reticulum stressed[1].

Product Specifications

CAS Number

[603-45-2]

UNSPSC

12352200

Hazard Statement

H315, H319

Target

Keap1-Nrf2

Type

Biochemical Assay Reagents

Related Pathways

NF-κB

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/rosolic-acid.html

Solubility

10 mM in DMSO

Smiles

C1=C(C=CC(=C1)O)C(=C2C=CC(=O)C=C2)C3=CC=C(C=C3)O

Molecular Formula

C19H14O3

Molecular Weight

290.31

Precautions

H315, H319

References & Citations

[1]Amin KN, et al. Effect of Rosolic acid on endothelial dysfunction under ER stress in pancreatic microenvironment. Free Radic Res. 2021 Jun;55 (6) :698-713.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Biochemical Assay Reagents

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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