Beta Defensin-3 (Human, Recombinant)

<strong>Beta Defensin-3 (Human, Recombinant)</strong>_x000D_ <strong>Catalog number:</strong> B2010345_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Volume/Weight:</strong> 10 ug_x000D_ <strong>pH:</strong> 7.4 upon reconstitution_x000D_ <strong>Supplied as:</strong> Lyophilized Powder_x000D_ <strong>Appearance:</strong> Powder_x000D_ <strong>Applications:</strong> highly pure Beta Defensin-3 (Human, Recombinant) expressed in E. coli. This protein acts as an antibacterial peptide that exhibits antibacterial activities towards Gram-negative and Gram-positive bacteria as well as an ability to act as a chemo-attractant._x000D_ <strong>Storage:</strong> -20C_x000D_ <strong>Keywords:</strong> rHuBD-3; DEFB-3; HBD3; Beta-defensin 103_x000D_ <strong>Grade:</strong> Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Para R, Romero R, Miller D, Panaitescu B, Varrey A, Chaiworapongsa T, Hassan_x000D_ SS, Hsu CD, Gomez-Lopez N. Human β-defensin-3 participates in intra-amniotic_x000D_ host defense in women with labor at term, spontaneous preterm labor and intact_x000D_ membranes, and preterm prelabor rupture of membranes. J Matern Fetal Neonatal_x000D_ Med. 2020 Dec;33(24):4117-4132._x000D_ _x000D_ 2: Li L, Jiang H, Chen R, Zhou J, Xiao Y, Zhang Y, Yan F. Human β-defensin 3_x000D_ gene modification promotes the osteogenic differentiation of human periodontal_x000D_ ligament cells and bone repair in periodontitis. Int J Oral Sci. 2020 Apr_x000D_ 29;12(1):13._x000D_ _x000D_ 3: Zhang Y, Zhao Y, Liu H, Yu W, Yang F, Li W, Cao Z, Wu Y. Mouse β-Defensin 3,_x000D_ A Defensin Inhibitor of Both Its Endogenous and Exogenous Potassium Channels._x000D_ Molecules. 2018 Jun 20;23(6):1489._x000D_ _x000D_ 4: Inthanachai T, Thammahong A, Edwards SW, Virakul S, Kiatsurayanon C,_x000D_ Chiewchengchol D. The Inhibitory Effect of Human Beta-defensin-3 on <i>Candida_x000D_ Glabrata</i> Isolated from Patients with Candidiasis. Immunol Invest. 2021_x000D_ Jan;50(1):80-91._x000D_ _x000D_ 5: Liu C, Pan B, Yang L, Wang B, Li J. Beta defensin 3 enhances ovarian_x000D_ granulosa cell proliferation and migration via ERK1/2 pathway in vitro†. Biol_x000D_ Reprod. 2019 Apr 1;100(4):1057-1065._x000D_ _x000D_ 6: Arora A, Majhi S, Mishra A. Antibacterial properties of human beta defensin-3_x000D_ derivative: CHRG01. J Biosci. 2018 Sep;43(4):707-715._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/31306193/">7: Follacchio GA, Pala A, Scaccianoce S, Monteleone F, Colletti PM, Rubello D,_x000D_ Liberatore M. In Vivo Microbial Targeting of 99mTc-Labeled Human β-Defensin-3 in_x000D_ a Rat Model of Infection. Clin Nucl Med. 2019 Nov;44(11):e602-e606. </a>_x000D_ _x000D_ <strong>Products Related to Beta Defensin-3 (Human, Recombinant) </strong> <a href="https://moleculardepot.com/product-category/Proteins/">: Proteins</a>