BG14
BG14 is a chemical optical modulation of epigenetic regulation of transcription (COMET) probe. BG14 enables high-resolution optical control of epigenetic mechanisms using visible light and can photochromically inhibit human histone deacetylases (HDACs) . BG14 can be used to study the dynamic regulation of the human genome[1].
Product Specifications
CAS Number
1628784-50-8
UNSPSC
12352005
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/bg14.html
Smiles
O=C(NC1=CC=CC=C1N)C2=CC=C(/N=N/C3=CC=C(N(C)C)C=C3)C=C2
Molecular Formula
C21H21N5O
Molecular Weight
359.42
References & Citations
[1]Reis S A, et al. Light-controlled modulation of gene expression by chemical optoepigenetic probes[J]. Nature chemical biology, 2016, 12 (5) : 317-323.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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