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Antimicrobial agent-2

Product Specifications

UNSPSC Description

Antimicrobial agent-2 (compound V-a) is a broad-spectrum antimicrobial agent, possessing inhibitory activity against various Gram-positive and -negative bacteria. Antimicrobial agent-2 has excellent inhibitory effect on Methicillin-resistant Staphylococcus aureus (MRSA) with a MIC of 1 μg/mL. Antimicrobial agent-2 can effectively damage the membrane and lead to the leakage of protein, also can induce the generation of ROS. Antimicrobial agent-2 exhibits low toxicity, no obvious resistance and good bioavailability[1].

Target Antigen

Reactive Oxygen Species

Type

Reference compound

Related Pathways

Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/antimicrobial-agent-2.html

Solubility

DMSO : 100 mg/mL (ultrasonic;warming;heat to 80°C)

Smiles

CO/N=C(C1=NC=CS1)/COC2=CC=C3C(C)=CC(OC3=C2)=O

Molecular Weight

330.36

References & Citations

[1]Yang XC, et al. Coumarin thiazoles as unique structural skeleton of potential antimicrobial agents. Bioorg Chem. 2022;124:105855.

Shipping Conditions

Room Temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-146460/Antimicrobial-agent-2-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-146460/Antimicrobial-agent-2-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

9007-83-4

Available Sizes

Curated Selection

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