Bupranolol

Bupranolol is an orally active, competitive and non-selective β-adrenoceptor antagonist without intrinsic sympathomimetic activity[1].

Product Specifications

CAS Number

[14556-46-8]

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/bupranolol.html

Purity

98.90

Solubility

DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

OC(CNC(C)(C)C)COC1=CC(C)=CC=C1Cl

Molecular Formula

C14H22ClNO2

Molecular Weight

271.78

Precautions

H315, H319, H335

References & Citations

[1]Chino D, et al. Pharmacological identification of β-adrenoceptor subtypes mediating isoprenaline-induced relaxation of guinea pig colonic longitudinal smooth muscle. J Smooth Muscle Res. 2018;54 (0) :13-27.|[2]Babu RJ, et al. Effect of cyclodextrins on the complexation and transdermal delivery of bupranolol through rat skin. Int J Pharm. 2004;271 (1-2) :155-165.