(R)-GSK866
Product Specifications
UNSPSC Description
(R)-GSK866 is the (R)-enantiomer of GSK866 (HY-157294). GSK866 is a selective agonist for glucocorticoid receptor with an IC50 of 4.6 nM[1].
Target Antigen
Glucocorticoid Receptor
Type
Reference compound
Related Pathways
Immunology/Inflammation;Vitamin D Related/Nuclear Receptor
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/r-gsk866.html
Smiles
NC1=C(C(NC[C@@](C(F)(F)F)(O)CN(CC)C(C2=C(C=CC=C2Cl)Cl)=O)=O)C=NN1C3=CC=C(C=C3)F
Molecular Weight
562.34
References & Citations
[1]Chandra S Chirumamilla, et al. Selective Glucocorticoid Receptor Properties of GSK866 Analogs with Cysteine Reactive Warheads. Front Immunol. 2017 Nov 1:8:1324.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-157294A/R-GSK866-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-157294A/R-GSK866-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1094607-80-3
Available Sizes
Curated Selection
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