DKI5
DKI5, also known as (E) -N’-benzylidenehydrazinecarbothiohydrazide, is a LOX-1 inhibitor with an IC50 value of 22.5 μM[1].
Product Specifications
CAS Number
[1101130-96-4]
UNSPSC
12352005
Target
LOX-1
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/dki5.html
Purity
98.12
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
NNC(N/N=C/C1=CC=CC=C1)=S
Molecular Formula
C8H10N4S
Molecular Weight
194.26
References & Citations
[1]Georgiou N, et al. Thiocarbohydrazone and Chalcone-Derived 3, 4-Dihydropyrimidinethione as Lipid Peroxidation and Soybean Lipoxygenase Inhibitors[J]. ACS Omega, 2023.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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