BML-288
Product Specifications
UNSPSC Description
BML-288 (compound Oxindole 1) is a potent PDE2 inhibitor with an IC50 value of 40 nM. BML-288 has the potential for the research of osteoarthritis pain[1].
Target Antigen
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bml-288.html
Smiles
O=C(C1C(N(C)C2=C1C=C(OC=C3)C3=C2)=O)NC4=NN=CS4
Molecular Weight
314.32
References & Citations
[1]Plummer MS, et al. Discovery of potent, selective, bioavailable phosphodiesterase 2 (PDE2) inhibitors active in an osteoarthritis pain model, part I: transformation of selective pyrazolodiazepinone phosphodiesterase 4 (PDE4) inhibitors into selective PDE2 inhibitors. Bioorg Med Chem Lett. 2013 Jun 1;23(11):3438-42.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-114023/BML-288-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-114023/
Clinical Information
No Development Reported
CAS Number
851681-89-5
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6472697-01 0.1 mL
DR3, ED (Wsl-1, Apo-3, TRAMP, LARD1-5, Death Receptor3) (MaxLight 490)
Ask
View Details 
MBS6472697-02 5x 0.1 mL
DR3, ED (Wsl-1, Apo-3, TRAMP, LARD1-5, Death Receptor3) (MaxLight 490)
Ask
View Details 
MBS7032568-01 0.02 mg
Recombinant Aliivibrio salmonicida Probable ubiquinone biosynthesis protein UbiB (ubiB)
Ask
View Details