RG13022
RG13022 is a tyrosine kinase inhibitor; inhibits the autophosphorylation reaction of the EGF receptor with an IC50 of 4 μM.
Product Specifications
CAS Number
136831-48-6
Product Name Alternative
Tyrphostin RG13022
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Neuroscience-Neuromodulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/RG13022.html
Purity
96.74
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
N#C/C(C1=CC=CN=C1)=C/C2=CC=C(OC)C(OC)=C2
Molecular Formula
C16H14N2O2
Molecular Weight
266.29
Precautions
H302, H315, H319, H335
References & Citations
[1]Yoneda T, et al. The antiproliferative effects of tyrosine kinase inhibitors tyrphostins on a human squamous cell carcinoma in vitro and in nude mice. Cancer Res. 1991 Aug 15;51 (16) :4430-5.|[2]Reddy KB, et al. Inhibition of breast cancer cell growth in vitro by a tyrosine kinase inhibitor. Cancer Res. 1992 Jul 1;52 (13) :3636-41.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
GTR10371875 96 Well
Human Complement C1q tumor necrosis factor related protein 6 (C1QTNF6) ELISA kit
Sign In for Pricing
View Details 
MBS066988 Inquire
Goose Epithelial Stromal Interaction 1, Breast ELISA Kit
Sign In for Pricing
View Details