(N-Me-Tyr1, N-Me-Arg7, D-Leu-NHEt8) -Dynorphin A (1-8)

(N-Me-Tyr1, N-Me-Arg7, D-Leu-NHEt8) -Dynorphin A (1-8) (E-2078), a stable Dynorphin A (1–8) (HY-P2159) analog, is a kappa opioid receptor (KOR) agonist[1].

Product Specifications

CAS Number

[103613-84-9]

Product Name Alternative

E2078

UNSPSC

12352209

Target

Opioid Receptor

Type

Peptides

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/n-me-tyr1-n-me-arg7-d-leu-nhet8-dynorphin-a-1-8.html

Solubility

H2O

Smiles

CCNC([C@@H](CC(C)C)NC([C@H](CCCNC(N)=N)N(C)C([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@@H](NC(CNC(CNC([C@@H](NC)CC1=CC=C(C=C1)O)=O)=O)=O)CC2=CC=CC=C2)=O)=O)=O)=O)=O

Molecular Formula

C50H81N15O9

Molecular Weight

1036.27

References & Citations

[1]Butelman ER, et al. Effects of E-2078, a stable dynorphin A (1-8) analog, on sedation and serum prolactin levels in rhesus monkeys. Psychopharmacology (Berl) . 1999 Nov;147 (1) :73-80.