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Phospho-Parkin (Ser65) Rabbit Polyclonal Antibody

Phospho-Parkin (Ser65) Rabbit Polyclonal Antibody

Product Specifications

Product Name Alternative

AR-JP; LPRS2; PARK2; PDJ; PRKN_HUMAN; PRKN; Parkin; Parkin RBR E3 ubiquitin-protein ligase; Parkinson juvenile disease protein 2 (Parkinson disease protein 2) ; 2.3.2.31; parkin RBR E3 ubiquitin protein ligase; Parkinson disease (autosomal recessive, juvenile) 2, parkin; parkinson protein 2, E3 ubiquitin protein ligase (parkin) ; E3 ubiquitin ligase; PRKN | Parkin (phospho-S65) ; p-Parkin; phospho-Parkin; p-PRKN; PRKN | Parkin (phospho-Ser65)

UniProt

O60260

Reactivity

Human, Mouse

Immunogen

KLH conjugated synthesised phosphopeptide derived from human Parkin around the phosphorylation site of Ser65 QQ (p-S) IV

Target

PRKN

Clonality

Polyclonal

Conjugation

Unconjugated

Field of Research

Signal Transduction

Purification

Affinity purified by Protein A

Concentration

1mg/ml

Dilution

WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500

Form

Liquid

Molecular Weight

50 kDa

References & Citations

Chakrabarti, Lina et al. Mitochondrial membrane potential-enriched CHO host: a novel and powerful tool for improving biomanufacturing capability MAbs, 14, 2020081 (2022), Jamie Whitfield 1, Alannah K A McKay 2, Nicolin Tee 2, Rachel McCormick 2, Aimee Morabito 2, Leonidas G Karagounis 2 3 4, Andréane M Fouassier 5, Davide D'Amico 5, Anurag Singh 5, Louise M Burke 2, John A Hawley 2 6 Evaluating the Impact of Urolithin A Supplementation on Running Performance, Recovery, and Mitochondrial Biomarkers in Highly Trained Male Distance Runners Sports Medicine, (2025), Huang, Yi-Fan et al. The protective effort of GPCR kinase 2-interacting protein-1 in neurons via promoting Beclin1-Parkin induced mitophagy at the early stage of spinal cord ischemia-reperfusion injury FASEB J, 34, 2055-2074 (2020), Yu, Shao-Hua et al. Human antigen R regulates hypoxia-induced mitophagy in renal tubular cells through PARKIN/BNIP3L expressions J Cell Mol Med, 25, 2691-2702 (2021), Lane, Sydney L. et al. Increased Systemic Antioxidant Power Ameliorates the Aging-Related Reduction in Oocyte Competence in Mice Int J Mol Sci, 22, 13019 (2021), Sun, Xin et al. Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy Acta Pharm Sin B, 12, 838-852 (2022), Zhang, Qin et al. Regulation of mitophagy through HIF-1?/miR-140-5p/PARKIN axis in acute kidney injury Environ Toxicol, 37, 1759-1767 (2022), Rai, Rajani et al. Distinct mechanism of cervical cancer cell death caused by the investigational new drug SHetA2 Front Oncol, 12, 958536 (2022), Singh, Anurag et al. Urolithin A improves muscle strength, exercise performance, and biomarkers of mitochondrial health in a randomized trial in middle-aged adults Cell Rep Med, 3, 100633 (2022), Chao, Tony et al. Burn-Induced Reductions in Mitochondrial Abundance and Efficiency are More Pronounced with Small Volumes of Colloids in Swine Am. J. Physiol., Cell Physiol., (2019)

Pubmed id

35030984, 40839339, 31908016, 33496385, 34884824, 35256949, 35312153, 36203464, 35584623, 31532719

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Prediction Reactivity

Bovine, Equine, Monkey, Porcine, Sheep

Tested Applications

IF, IHC-Fr, IHC-P, WB

Host or Source

Rabbit

Preservative

0.01M TBS (pH7.4) with 1% rAlbumin, 0.02% Proclin300 and 50% Glycerol.

Isotype

IgG

Available Sizes

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