ML3403
ML3403 is a potent p38 MAPK inhibitor with an IC50 of 0.38 μM[1].
Product Specifications
CAS Number
549505-65-9
UNSPSC
12352005
Target
P38 MAPK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ml3403.html
Purity
99.28
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(NC1=NC=CC(C2=C(C3=CC=C(F)C=C3)N=C(SC)N2)=C1)C4=CC=CC=C4
Molecular Formula
C23H21FN4S
Molecular Weight
404.50
References & Citations
[1]Kammerer B, et al. Pharmacokinetics of ML3403 ({4-[5- (4-fluorophenyl) -2-methylsulfanyl-3H-imidazol-4-yl]-pyridin-2-yl}- (1-phenylethyl) -amine), a 4-Pyridinylimidazole-type p38 mitogen-activated protein kinase inhibitor. Drug Metab Dispos. 2007 Jun;35 (6) :875-83.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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