Amlodipine aspartic acid impurity

Amlodipine aspartic acid impurity (Amlodipine aspartate) is the impurity of Amlodipine aspartic acid. Amlodipine aspartic acid is a calcium channel blocker with antihypertensive and antianginal properties. Amlodipine aspartic acid impurity can control blood pressure. Amlodipine aspartic acid impurity corrects gut dysbiosis and enhances taurine and hypotaurine metabolism. Amlodipine aspartic acid impurity can be studied in research for NAFLD and hypertension[1][2].

Product Specifications

CAS Number

[400602-35-9]

Product Name Alternative

Amlodipine aspartate

UNSPSC

12352209

Target

Calcium Channel; Drug Metabolite

Type

Peptides

Related Pathways

Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/amlodipine-aspartic-acid-impurity.html

Purity

99.42

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(C1=C(COCCNC(C(O)=O)CC(O)=O)NC(C)=C(C(OC)=O)C1C2=CC=CC=C2Cl)OCC

Molecular Formula

C24H29ClN2O9

Molecular Weight

524.95

References & Citations

[1]Sheraz MA, et al. Formulations of Amlodipine: A Review. J Pharm (Cairo) . 2016;2016:8961621.|[2]Li, Y., et al., (2022) . Amlodipine, an anti-hypertensive drug, alleviates non-alcoholic fatty liver disease by modulating gut microbiota. British journal of pharmacology, 179 (9), 2054–2077.