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Vatanidipine (hydrochloride)

Vatanidipine (Watanidipine) hydrochloride is an orally active dihydropyridine (DHP) -type calcium channel blocker and a useful antihypertensive agent. Vatanidipine hydrochloride shows vasodilatory effects and also suppresses noradrenaline release from sympathetic nerve endings[1][2].

Product Specifications

CAS Number

133743-71-2

Product Name Alternative

Watanidipine (hydrochloride) ; AE0047

UNSPSC

12352005

Target

Calcium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Field of Research

Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/vatanidipine-hydrochloride.html

Smiles

O=C(C1=C(C)NC(C)=C(C(OC)=O)C1C2=CC([N+]([O-])=O)=CC=C2)OCCC3=CC=C(N4CCN(C(C5=CC=CC=C5)C6=CC=CC=C6)CC4)C=C3.Cl.Cl

Molecular Formula

C41H44Cl2N4O6

Molecular Weight

759.72

References & Citations

[1]Matsumura Y, et al. Vatanidipine hydrochloride: a new long-lasting antihypertensive agent. Expert Opin Investig Drugs. 2001 Jan;10 (1) :139-55.|[2]H Shinyama, et al. Effects of the calcium antagonist AE0047 on the development of neurological deficit and infarction after middle cerebral artery occlusion in stroke-prone spontaneously hypertensive rats. J Pharm Pharmacol. 1997 Sep;49 (9) :919-24.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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