N-Acetyl-L-glutamic acid

N-Acetyl-L-glutamic acid is a type of glutamic acid that can serve as a component of cell culture media. When combined with media containing inorganic salts, carbohydrates, vitamins, and amino acids, N-Acetyl-L-glutamic acid plays roles in promoting cell growth, enhancing antibody production, etc. N-Acetyl-L-glutamic acid is also an endogenous metabolite that can be found in the brain. Additionally, as an IgE blocker, N-Acetyl-L-glutamic acid can be used in the research of allergic diseases[1][2][3].

Product Specifications

CAS Number

[1188-37-0]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/n-acetyl-l-glutamic-acid.html

Concentration

10mM

Purity

98.0

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 25 mg/mL (ultrasonic)

Smiles

O=C(O)CC[C@@H](C(O)=O)NC(C)=O

Molecular Formula

C7H11NO5

Molecular Weight

189.17

Precautions

H302, H315, H319, H335

References & Citations

[1]M Hashimoto, et al. Animal cell culturing media containing N-acetyl-L-glutamic acid. Patent. US5719050A. 1998-02-17.|[2]Auditore JV, et al. Occurrence of N-acetyl-L-glutamic acid in the human brain. J Neurochem. 1966 Nov;13 (11) :1149-55.|[3]de Campos-Mesquita D M, et al. Blocking IgE with L-glutamic acid analogs as an alternative approach to allergy treatment. European Journal of Biological Research, 2023, 13 (1) : 31-40.