NPI52
NPI52 (Compound E1) is a foot-and-mouth disease virus 3C protease (FMDV 3Cpro) inhibitor, with IC50 values of 0.05 and 0.11 µM in FRET and cell-based assay, respectively[1].
Product Specifications
CAS Number
1429218-68-7
UNSPSC
12352005
Target
Virus Protease
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/npi52.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@@H](CC1=C(C=CC=C2)C2=CC=C1)C(N[C@@H](CC(C)C)C(N[C@@H](C[C@H]3C(NCC3)=O)C=O)=O)=O)OCC4=CC=CC=C4
Molecular Formula
C34H40N4O6
Molecular Weight
600.70
References & Citations
[1]Kim Y, et al. Potent small molecule inhibitors against the 3C protease of foot-and-mouth disease virus. Microbiol Spectr. 2024 Mar 11:e0337223.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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