Purified Anti-Human CD154 Antibody[24-31]

CD154 (CD40 ligand) is also known as CD40L, gp39, TRAP and T-BAM. CD40 ligand is a 32-39 kD type II transmembrane glycoprotein. It is a member of the TNF superfamily and is expressed on activated T cells. It has been reported to be important for B cell costimulation following binding of its receptor, CD40. Additionally, binding of CD40L to CD40 on B cells promotes the secretion of immunoglobulin and Ig isotype switching. CD40L is also involved in the regulation of cytokine production by T cells.

IMD; HIGM; T-Cell Antigen Gp; Tumor Necrosis Factor Ligand Superfamily Member; TNFSF; CD154; CD40L; HIGM1; IGM; IMD3; T-BAM; TNFSF5; TRAP; gp39; hCD40L; CD40LG; CD40 Ligand; CD40-L; T-Cell Antigen Gp39; TNF-Related Activation Protein; Tumor Necrosis Factor Ligand Superfamily Member 5; T-BAM; gp39; TRAP; TNFSF5; TNFSF5; CD40LG