BMS-457

BMS-457 is a potent and selective CCR1 antagonist. BMS-457 can be used in the study of rheumatoid arthritis[1].

Product Specifications

CAS Number

[946594-19-0]

UNSPSC

12352101

Target

CCR

Type

Reference compound

Related Pathways

GPCR/G Protein; Immunology/Inflammation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/bms-457.html

Smiles

O[C@@]1(C2=CC=C(C=C2)Cl)C(C)(CN(CC1)C([C@@H](C(C)C)NC([C@@H]3CC[C@H](C3)O)=O)=O)C

Molecular Formula

C24H35ClN2O4

Molecular Weight

451.00

References & Citations

[1]Gardner DS, et al. The discovery of BMS-457, a potent and selective CCR1 antagonist. Bioorg Med Chem Lett. 2013 Jul 1;23 (13) :3833-40.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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