Ethyl 5-hydroxy-2-methyl-1H-indole-3-carboxylate

Ethyl 5-hydroxy-2-methyl-1H-indole-3-carboxylate is an active compound, and can be used in the synthesis of 2-phenylthiomethyl-indole derivatives, 2-phenylthiomethyl-indole derivative is a 5-lipoxygenase (5-LO) inhibitor[1].

Product Specifications

CAS Number

[7598-91-6]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Lipoxygenase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/ethyl-5-hydroxy-2-methyl-1h-indole-3-carboxylate.html

Concentration

10mM

Purity

99.91

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CCOC(C(C1=C2C=CC(O)=C1)=C(N2)C)=O

Molecular Formula

C12H13NO3

Molecular Weight

219.24

Precautions

H302, H315, H319, H335

References & Citations

[1]Peduto A, et al. Further studies on ethyl 5-hydroxy-indole-3-carboxylate scaffold: design, synthesis and evaluation of 2-phenylthiomethyl-indole derivatives as efficient inhibitors of human 5-lipoxygenase. Eur J Med Chem. 2014 Jun 23;81:492-8.