1-Stearoyl-2-15 (S) -HETE-sn-glycero-3-PE

1-Stearoyl-2-15 (S) -HETE-sn-glycero-3-PE (15 (S) -HETE-SAPE) is a phospholipid containing stearic acid (HY-B2219) at the sn-1 position and 15 (S) -HETE (HY-113336) at the sn-2 position. 1-Stearoyl-2-15 (S) -HETE-sn-glycero-3-PE is formed by direct oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PE (SAPE) by 15-LOX in human peripheral mononuclear cells activated with the calcium ionophore A23187 (HY-N6687) .

Product Specifications

CAS Number

[947381-58-0]

Product Name Alternative

15 (S) -HETE-SAPE; 15 (S) -Hydroxyeicosatetraenoic acid-SAPE; 1-Stearoyl-2-15 (S) -HETE-sn-glycero-3-Phosphatidylethanolamine

UNSPSC

12352211

Hazard Statement

H225-H319

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/1-stearoyl-2-15-s-hete-sn-glycero-3-pe.html

Smiles

NCCOP(OC[C@H](OC(CCC/C=C\C/C=C\C/C=C\C=C\[C@@H](O)CCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O)(O)=O

Molecular Formula

C43H78NO9P

Molecular Weight

784.05

Precautions

P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P370+P378-P403+P235-P501

References & Citations

[1]Maskrey, et al. Activated platelets and monocytes generate four hydroxyphosphatidylethanolamines via lipoxygenase. J. Biol. Chem. 282 (28), 20151-20163 (2007) .