α-Chaconine
α-Chaconine inhibits the expressions of COX-2, IL-1β, IL-6, and TNF-α at the transcriptional level. α-Chaconine inhibits the LPS-induced expressions of iNOS and COX-2 at the protein and mRNA levels and their promoter activities in RAW 264.7 macrophages. Anti-inflammatory effects[1].
Product Specifications
CAS Number
[20562-03-2]
UNSPSC
12352005
Hazard Statement
H302, H361
Target
COX
Type
Natural Products
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/alpha-chaconine.html
Purity
99.76
Solubility
DMSO : 33.33 mg/mL (ultrasonic)
Smiles
C[C@@]12[C@](C[C@@]3([H])[C@]2([H])[C@@H]([C@]4([H])N3C[C@@H](C)CC4)C)([H])[C@@]5([H])[C@]([C@@]6(C(C[C@@H](O[C@@]7([H])[C@@H]([C@H]([C@H](O[C@@]8([H])[C@@H]([C@@H]([C@@H](O)[C@H](C)O8)O)O)[C@@H](CO)O7)O)O[C@@]9([H])[C@@H]([C@@H]([C@@H](O)[C@H](C)O9)O)O)CC6)=CC5)C)([H])CC1
Molecular Formula
C45H73NO14
Molecular Weight
852.06
Precautions
H302, H361
References & Citations
Solanum tuberosum
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
COX-2
Available Sizes
Curated Selection
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