NOTA-bis (tBu) ester
NOTA-bis (tBu) ester (NOTA-bis (t-Butyl ester) ), a NOTA derivative, is a bifunctional chelator that can be used for drug coupling[1].
Product Specifications
CAS Number
[1161415-28-6]
Product Name Alternative
NOTA-bis (t-Butyl ester)
UNSPSC
12352200
Hazard Statement
H315, H319
Target
Biochemical Assay Reagents; Radionuclide-Drug Conjugates (RDCs)
Type
Biochemical Assay Reagents
Related Pathways
Antibody-drug Conjugate/ADC Related; Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nota-bis-tbu-ester.html
Purity
98.0
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(CN1CCN(CCN(CC1)CC(OC(C)(C)C)=O)CC(OC(C)(C)C)=O)O
Molecular Formula
C20H37N3O6
Molecular Weight
415.52
Precautions
H315, H319
References & Citations
[1]Haojun Chen, et al. Novel "Add-On" Molecule Based on Evans Blue Confers Superior Pharmacokinetics and Transforms Drugs to Theranostic Agents. J Nucl Med. 2017 Apr;58 (4) :590-597.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported
Isoform
RDC Bifunctional Chelator
Available Sizes
Curated Selection
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