NOTA-bis (tBu) ester
NOTA-bis (tBu) ester (NOTA-bis (t-Butyl ester) ), a NOTA derivative, is a bifunctional chelator that can be used for drug coupling[1].
Product Specifications
CAS Number
1161415-28-6
Product Name Alternative
NOTA-bis (t-Butyl ester)
UNSPSC
12352200
Hazard Statement
H315, H319
Target
Biochemical Assay Reagents; Radionuclide-Drug Conjugates (RDCs)
Type
Biochemical Assay Reagents
Related Pathways
Antibody-drug Conjugate/ADC Related; Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nota-bis-tbu-ester.html
Purity
98.0
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(CN1CCN(CCN(CC1)CC(OC(C)(C)C)=O)CC(OC(C)(C)C)=O)O
Molecular Formula
C20H37N3O6
Molecular Weight
415.52
Precautions
H315, H319
References & Citations
[1]Haojun Chen, et al. Novel "Add-On" Molecule Based on Evans Blue Confers Superior Pharmacokinetics and Transforms Drugs to Theranostic Agents. J Nucl Med. 2017 Apr;58 (4) :590-597.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported
Isoform
RDC Bifunctional Chelator
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC880965-500 1x 500 µL
MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (VU-11D1), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC471925-100 1x 100 µL
P53 Tumor Suppressor Protein (PCRP-TP53-1F7), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details