Ligustrazine (hydrochloride)

Ligustrazine (hydrochloride) is a natural product. IC50 value: Target: In vitro: Ligustrazine hydrochloride displayed a protection effect on injured ECV304 cells, NOS and NO formation were significantly increased compared with the model group [1]. In vivo:

Product Specifications

CAS Number

[76494-51-4]

Product Name Alternative

Chuanxiongzine (hydrochloride) ; Tetramethylpyrazine (hydrochloride)

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Others

Type

Natural Products

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/Ligustrazine-hydrochloride.html

Purity

99.92

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

Smiles

C1(C)=NC(C)=C(C)N=C1C.C

Molecular Formula

C8H12N2.xHCl

Precautions

H302, H315, H319, H335

References & Citations

[1]Dongming Xu, et al. Protective effect of ligustrazine hydrochloride on homocysteine-injured ECV304 cells. Zhongguo Zhong Yao Za Zhi. 2012 Jun;37 (12) :1836-9.|[2]Wang Q, et al. Brain microdialysate, CSF and plasma pharmacokinetics of ligustrazine hydrochloride in rats after intranasal and intravenous administration. Biopharm Drug Dispos. 2013 Oct;34 (7) :417-22.