5-Methyl-2′-O-methylcytidine
5-Methyl-2′-O-methylcytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
[113886-70-7]
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Nucleoside Antimetabolite/Analog
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/5-methyl-2-o-methylcytidine.html
Purity
99.76
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O[C@H]1[C@@H](OC)[C@H](N2C(N=C(N)C(C)=C2)=O)O[C@@H]1CO
Molecular Formula
C11H17N3O5
Molecular Weight
271.27
Precautions
H302, H315, H319
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room Temperature
Storage Conditions
RT, protect from light, stored under nitrogen
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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