CO23
CO23 is a selective thyroid hormone receptor (TR) α agonist and used for growth and development regulation. CO23 was able to be transported through the blood-brain barrier[1].
Product Specifications
CAS Number
1370363-74-8
UNSPSC
12352005
Target
Thyroid Hormone Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/co23.html
Purity
98.00
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C1NC(C(CC2=CC(I)=C(OC3=CC=C(O)C(C(C)C)=C3)C(I)=C2)N1)=O
Molecular Formula
C19H18I2N2O4
Molecular Weight
592.17
References & Citations
[1]Grijota-Martínez C, et al. In vivo activity of the thyroid hormone receptor beta- and α-selective agonists GC-24 and CO23on rat liver, heart, and brain. Endocrinology. 2011 Mar;152 (3) :1136-42.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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