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CO23

CO23 is a selective thyroid hormone receptor (TR) α agonist and used for growth and development regulation. CO23 was able to be transported through the blood-brain barrier[1].

Product Specifications

CAS Number

1370363-74-8

UNSPSC

12352005

Target

Thyroid Hormone Receptor

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Endocrinology

Assay Protocol

https://www.medchemexpress.com/co23.html

Purity

98.00

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

O=C1NC(C(CC2=CC(I)=C(OC3=CC=C(O)C(C(C)C)=C3)C(I)=C2)N1)=O

Molecular Formula

C19H18I2N2O4

Molecular Weight

592.17

References & Citations

[1]Grijota-Martínez C, et al. In vivo activity of the thyroid hormone receptor beta- and α-selective agonists GC-24 and CO23on rat liver, heart, and brain. Endocrinology. 2011 Mar;152 (3) :1136-42.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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