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Bis-PEG10-acid

Bis-PEG10-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

Product Specifications

CAS Number

[2055023-26-0]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/bis-peg10-acid.html

Purity

98.0

Solubility

10 mM in DMSO

Smiles

O=C(O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O

Molecular Formula

C24H46O14

Molecular Weight

558.61

Precautions

H302, H315, H319, H335

References & Citations

[1]Zhao Q, et al. Discovery of SIAIS178 as an Effective BCR-ABL Degrader by Recruiting Von Hippel-Lindau (VHL) E3 Ubiquitin Ligase. J Med Chem. 2019 Oct 24;62 (20) :9281-9298.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PEG Linkers

Available Sizes

Curated Selection

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