WL12
WL12 is a specifically targeting programmed death ligand 1 (PD-L1) binding peptide. WL12 can be radiolabeled by different radionuclides, generating radiotracers, which can assess the tumor PD-L1 expression[1].
Product Specifications
CAS Number
1886057-64-2
UNSPSC
12352209
Target
PD-1/PD-L1; Radionuclide-Drug Conjugates (RDCs)
Type
Peptides
Related Pathways
Antibody-drug Conjugate/ADC Related; Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/wl12.html
Purity
99.99
Solubility
H2O : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
C(C=1C=2C(N(C)C1)=CC=CC2)[C@H]3C(=O)N(C)[C@@H](CCCC)C(=O)N(C)[C@@H](CCCC)C(=O)N[C@@H](CCCN)C(=O)N[C@H](C(NCC(N)=O)=O)CSCC(=O)N[C@@H](CC4=CC=C(O)C=C4)C(=O)N(C)[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(=O)N5[C@](C(=O)N[C@@H](CC6=CN=CN6)C(=O)N[C@@H](CC(C)C)C(=O)N7[C@](C(=O)N[C@@H](CC=8C=9C(NC8)=CC=CC9)C(=O)N[C@@H](CO)C(=O)N3)(C[C@@H](O)C7)[H])(CCC5)[H]
Molecular Formula
C91H128N22O20S
Molecular Weight
1882.19
References & Citations
[1]Jiang J, et al. Noninvasive evaluation of PD-L1 expression using Copper 64 labeled peptide WL12 by micro-PET imaging in Chinese hamster ovary cell tumor model. Bioorg Med Chem Lett. 2021 May 15;40:127901.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
RDC Peptide
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS7234308-01 48 Well
Canine 5, 6-dihydroxyindole-2-carboxylic acid oxidase (TYRP1) ELISA Kit
Sign In for Pricing
View Details MBS7234308-02 96 Well
Canine 5, 6-dihydroxyindole-2-carboxylic acid oxidase (TYRP1) ELISA Kit
Sign In for Pricing
View Details