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Ethyl cinnamate (Standard)

Ethyl cinnamate (Standard) is the analytical standard of Ethyl cinnamate. This product is intended for research and analytical applications. Ethyl cinnamate, an orally active chemical constituent of the rhizome of Kaempferia galanga, exhibits anti-cancer, nematocidal, sedative and vasorelaxant activities. Ethyl cinnamate is a fragrance ingredient used as a food flavor and additive for cosmetic products. Ethyl cinnamate is also an excellent clearing reagent for mammalian tissues. Ethyl cinnamate suppresses tumor growth through anti-angiogenesis by attenuating VEGFR2 signal pathway in colorectal cancer. Ethyl cinnamate inhibits the tonic contractions induced by high K+ and phenylephrine (PE) with respective IC50 values of 0.30 mM and 0.38 mM in rat aorta[1][2][3][4].

Product Specifications

CAS Number

103-36-6

UNSPSC

12352005

Target

Apoptosis; Parasite; Reference Standards; VEGFR

Type

Reference Standards

Related Pathways

Anti-infection; Apoptosis; Others; Protein Tyrosine Kinase/RTK

Field of Research

Cancer; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/ethyl-cinnamate-standard.html

Smiles

O=C(OCC)/C=C/C1=CC=CC=C1

Molecular Formula

C11H12O2

Molecular Weight

176.21

References & Citations

[1]S P Bhatia, et al. Fragrance material review on ethyl cinnamate. Food Chem Toxicol. 2007;45 Suppl 1:S90-4.|[2]Anika Klingberg, et al. Fully Automated Evaluation of Total Glomerular Number and Capillary Tuft Size in Nephritic Kidneys Using Lightsheet Microscopy. J Am Soc Nephrol. 2017 Feb;28 (2) :452-459.|[3]Wang S, et al. Ethyl cinnamate suppresses tumor growth through anti-angiogenesis by attenuating VEGFR2 signal pathway in colorectal cancer. J Ethnopharmacol. 2024 May 23;326:117913. |[4]Othman R, et al. Vasorelaxant effects of ethyl cinnamate isolated from Kaempferia galanga on smooth muscles of the rat aorta. Planta Med. 2002 Jul;68 (7) :655-7.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

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