Pyruvic acid-13C-1 (sodium)

Sodium 2-oxopropanoate-13C is the 13C labeled Sodium 2-oxopropanoate[1]. Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS[2][3].

Product Specifications

CAS Number

[124052-04-6]

Product Name Alternative

Sodium 2-oxopropanoate-13C; Acetylformic acid-13C-1 (sodium)

UNSPSC

12352211

Hazard Statement

H317, H319

Target

Endogenous Metabolite; Reactive Oxygen Species (ROS)

Type

Isotope-Labeled Compounds

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/sodium-2-oxopropanoate-13c.html

Purity

98.90

Solubility

10 mM in DMSO

Smiles

O=C(O[Na])C([13CH3])=O

Molecular Formula

C2 13CH3NaO3

Molecular Weight

111.04

Precautions

H317, H319

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]S Nemoto, et al. Role for mitochondrial oxidants as regulators of cellular metabolism. Mol Cell Biol. 2000 Oct;20 (19) :7311-8.|[3]W Zhao, et al. Fructose induced deactivation of antioxidant enzymes: preventive effect of pyruvate. Free Radic Res. 2000 Jul33 (1) :23-30.