Adrenalone (hydrochloride)

Adrenalone hydrochloride is an adrenergic agonist used as a topical vasoconstrictor and hemostatic. Adrenalone hydrochloride is an inhibitor of dopamine β oxidase. Adrenalone hydrochloride is chemically similar to known norepinephrine transporter (NET) ligands with an IC50 of 36.9 μM[1][2].

Product Specifications

CAS Number

[62-13-5]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Endocrinology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/Adrenalone-hydrochloride.html

Purity

99.88

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : ≥ 50 mg/mL

Smiles

CNCC(C1=CC=C(O)C(O)=C1)=O.[H]Cl

Molecular Formula

C9H12ClNO3

Molecular Weight

217.65

Precautions

H302, H315, H319, H335

References & Citations

[1]M GOLDSTEIN, et al. Inhibition of dopamine beta oxidase by adrenalone. Nature.1961 Dec 16;192:1081.|[2]Avner Schlessinger, et al. Structure-based discovery of prescription drugs that interact with the norepinephrine transporter, NET. Proc Natl Acad Sci U S A. 2011 Sep 20;108 (38) :15810-5.